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Effectiveness of Recombinant Laryngotracheitis Virus Vaccines

09 March 2011

Both recombinant vaccines (HVT-LT + FPV-LT) provided broilers with similar protection to conventional vaccines, according to Dr James S. Guy and Isabel M. Gimeno and Melissa West of the College of Veterinary Medicine of the North Carolina State University.

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Laryngotracheitis (LT) is a highly contagious, respiratory tract infection of chickens. The disease results in significant economic losses due to impaired flock performance, increased mortality and decreased egg production, explain Dr Guy and co-authors. In recent years, the disease has occurred with increased frequency, primarily in boiler chickens, despite increased usage of modified-live virus vaccines.

Vaccines based on recombinant DNA technology recently have been developed for LT control. Recombinant LT vaccines provide opportunities for development of improved control procedures; however, little is known about their effectiveness. The purpose of the present study, according to the authors, was to evaluate the effectiveness of commercially available recombinant virus-vectored LT vaccines, and to determine whether these vaccines might be used in combination with CEO vaccines to prevent the adverse effects associated with CEO products.

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