converting website visitors - news, features, articles and disease information for the poultry industry

Featured Articles

Effects of Dietary DDGS on Growth, Oxidative Stress and Immune Function in Broilers

06 April 2015

This Chinese study reveals that corn distillers dried grains with solubles (DDGS) included in a broiler diet at a level of 15 per cent had some beneficial effects on immune functions in the birds for broilers to some degree, without adversely affecting growth.

DDGS contain relatively large amounts of polyunsaturated fatty acids and some yeast components, which may increase oxidative stress and alter immune function, respectively, when fed to broilers, according to F.Z. Lui and colleagues at Northwest A&F University in Yangling, China.

So they undertook a study, published in Journal of Applied Poultry Research, to assess the effects of DDGS on broilers under immunosuppressive challenge.

A total of 300 day-old male broiler chickens were assigned to two treatments with six replicates pre-treatment.

Birds were fed diets formulated to contain 0 or 15 per cent corn-based DDGS, respectively.

Chickens were then randomly allotted to one of four treatment groups:

  1. negative control (NC) corn-soybean meal diet without dexamethasone (DEX) challenge
  2. positive control (PC) corn-soybean meal diet with (DEX) challenge
  3. 15 per cent DDGS without DEX challenge (D)
  4. 15 per cent DDGS with DEX (D+DEX).

The experimental diets were fed for six weeks in two phases. On day 21, serum IgA, IgG content and malondialdehyde (MDA), glutathione peroxidase (GSHPx), total superoxide dismutase (T-SOD), and total antioxidant activity (T-AOC) capacity were analysed.

Based on these results, dietary DDGS did not influence average daily gain, average daily feed intake or feed:gain ratio 21-, 28- or 42-day-old chicks (P>0.05), however, DEX affected average daily gain and feed:gain ratio of 28-day-old chicks significantly (P<0.05).

The researchers found that dietary DDGS enhanced humoral immunity but had no effect on the systemic response to DEX.

Beneficial effects were observed from feeding a diet containing 15 per cent DDGS on immunoglobulins IgA and IgG, as well as the expression of interleukins in the spleen.


Min Y.N., L.L. Li, S.K. Liu, J. Zhang, Y.P. Gao and F.Z. Liu. 2015. Effects of dietary distillers dried grains with solubles (DDGS) on growth performance, oxidative stress and immune function in broiler chickens. J. Appl. Poult. Res. 24:23-29.

Further Reading

You can view the full report by clicking here.

April 2015

Our Sponsors


Seasonal Picks

Animal Welfare Science, Husbandry and Ethics: The Evolving Story of Our Relationship with Farm Animals