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Feeding Broilers to Up-Regulate Genes for Anti-NDV Activity

14 January 2015
Diamond V

US - Newcastle disease virus (NDV) can be lethal to poultry or weaken birds’ immune defences against other disease, says Diamond V.

Previously published research indicates that feeding Diamond V Original XPC™ results in an improvement in vaccine titres, suggesting enhanced antibody production and potential increased protection against NDV.

More recent research at Texas A&M University in the USA focused on the mechanism behind increased antibody titres, a function of the adaptive immune system. An initial report in the Diamond V PoultryAdvisor newsletter (November 2014) described how feeding Original XPC increased antibody titres and immune markers.

The continuation of that research, also published in PoultryAdvisor (December 2014), showed that genes associated with anti-viral activities and the Th1 immune response (cell-mediated immunity) were significantly up-regulated in broilers fed Original XPC.

The Texas A&M researchers also suggested that such supplementation may promote early development of the central immune organs [click here].

The International Poultry Scientific Forum on 26 and 27 January in Atlanta, USA, includes two presentations on the effects of Original XPC supplementation on adaptive immune function and immune gene expression in broilers.

Seven other presentations at the 2015 IPSF also involve Diamond V researchers, products and poultry industry expertise [click here].

The Diamond V Poultry Team will be on hand in Atlanta for the International Production and Processing Expo (IPPE) on booth A431 from 27 to 29 January.

To subscribe to the free Diamond V PoultryAdvisor newsletter or for more on Diamond V poultry research, visit

Further Reading

Find out more information on Newcastle disease by clicking here.

ThePoultrySite News Desk

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