Histopathology and Cytology of
By Ivan Dinev, DVM, PhD
IONOPHORE TOXICITY CHICKENS
Fig. 1. & Fig. 2. Transverse/londitudinal cross-section, thigh muscle, chicken, after intoxication with high doses maduramycin. Enhanced eosinophilia and denenerative necrobiotic lesions of muscle fibres. H/E, Bar = 40 µm.
Fig. 3. Longitudinal cross-section, thigh muscle, chicken, after intoxication with high doses maduramycin. Appearance of macrophages and initial organization of necrotic detritus occuring after muscle fibre breakdown. H/E, Bar = 50 µm.
Fig. 4. Inflammatory, degenerative necrobiotic lesions and urate deposits in renal tubules. H/E, Bar = 25 µm.
Fig. 5. Urate cylinders (arrow) and retention cysts (rc) in kidneys. H/E, Bar = 50 µm.
Fig. 6. Degenerative necrobiotic lesions of the liver. H/E, Bar = 50 µm.