A proven reference for the reduction of Newcastle disease

Commercial poultry production is facing many health challenges, including respiratory ones. As a consequence, mitigation or reduction of virus circulation in between houses or farms is of paramount importance to keep the respiratory tract healthy and be able to reach one’s production targets. Besides biosecurity, there is a need to get access to vaccines with the best features in terms of protection, but also prevention against the uncontrolled circulation of avian paramyxovirus type 1, also known as Newcastle disease virus (ND virus) in its pathogenic (‘velogenic’) form.
calendar icon 17 August 2021
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Figure 1. Kinetics of velogenic NDV shedding in vaccinated and unvaccinated birds after direct infection (seeder subgroups) or contact infection (contact subgroups). Seeder subgroups were challenged with 5.0 log10ELD50 of velogenic NDV intra-nasally. Contacts were co-mingled with seeders from 8 hours post-challenge. Oro-nasal swabs and cloacal swabs were collected daily for 14 days post-challenge; vNDV amount was quantified by RT-qPCR. Individual results and mean & STD of Ct values are shown.
Figure 1. Kinetics of velogenic NDV shedding in vaccinated and unvaccinated birds after direct infection (seeder subgroups) or contact infection (contact subgroups). Seeder subgroups were challenged with 5.0 log10ELD50 of velogenic NDV intra-nasally. Contacts were co-mingled with seeders from 8 hours post-challenge. Oro-nasal swabs and cloacal swabs were collected daily for 14 days post-challenge; vNDV amount was quantified by RT-qPCR. Individual results and mean & STD of Ct values are shown.

Seeder Groups

Figure 1. Kinetics of velogenic NDV shedding in vaccinated and unvaccinated birds after direct infection (seeder subgroups) or contact infection (contact subgroups). Seeder subgroups were challenged with 5.0 log10ELD50 of velogenic NDV intra-nasally. Contacts were co-mingled with seeders from 8 hours post-challenge. Oro-nasal swabs and cloacal swabs were collected daily for 14 days post-challenge; vNDV amount was quantified by RT-qPCR. Individual results and mean & STD of Ct values are shown.
Figure 1. Kinetics of velogenic NDV shedding in vaccinated and unvaccinated birds after direct infection (seeder subgroups) or contact infection (contact subgroups). Seeder subgroups were challenged with 5.0 log10ELD50 of velogenic NDV intra-nasally. Contacts were co-mingled with seeders from 8 hours post-challenge. Oro-nasal swabs and cloacal swabs were collected daily for 14 days post-challenge; vNDV amount was quantified by RT-qPCR. Individual results and mean & STD of Ct values are shown.

Contact Groups

References
References
[1] Tatár-Kis T, Fischer EAJ, Cazaban C, Walkó-Kovács E, Homonnay ZG, Velkers FC, Palya V, Stegeman JA. A Herpesvirus of Turkey-Based Vector Vaccine Reduces Transmission of Newcastle Disease Virus in Commercial Broiler Chickens with Maternally Derived Antibodies. Vaccines (Basel). 2020 Oct 16;8(4):614. doi: 10.3390/vaccines8040614. PMID: 33081359; PMCID: PMC7720113.

Mustafa Seçkin Sandikli

Global Marketing Manager at Ceva
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