The effects of 1.25 ppm T-2 toxin on performance, lesions and general health of male broiler
T-2 toxin is a mycotoxin of the group of trichothecenes produced by fungi of the Fusarium genus i.e Fusarium acuminatum, Fusarium poae, Fusarium sporotrichioides and Stachybotrys chartarum commonly found in various cereal crops (wheat, corn, barley, oats, rye etc.) but also in soy meal.
27 April 2009
3 minute read
Trichothecenes are in general very stable compounds, both during storage/milling and processing of feed and they do not degrade at high temperatures (pelletizing, extruding). They interfere with the protein production, thus damaging any process depending on protein synthesis such as growth and reproduction. Their negative impact on the immune system is also already proven. Additionally, T-2 toxin and diacetoxiscirpenol (DAS) are strong dermatotoxins which cause lesions and necrosis of skin and tissues.
Aim of the Trial
The aim of the trial was to evaluate the effect of 1.25 ppm T-2 toxin on performance and health of growing male broiler chickens. Additionally, the efficacy of 1 and 1.5 kg of Mycofix® Select to counteract T-2 toxin was tested.
Materials and Methods
The trial was made in the experimental units of the International Institute of Animal Investigation (iiia) in Queretaro, Mexico, under the surveillance of Dr. Miguel Forat. Ninety Ross 308 male broilers were weighed and randomly assigned to 6 groups, 1 bird per cage and 18 birds per group (Picture 1). The trial started at day 10 of age and lasted until day 39 of age of the birds. Prior to start, birds were fed a pre-starter diet, and during the trial a grower diet based on corn, soya paste and soy oil meeting the NRC requirements, with a crude protein of 20% and providing 3000 kcal. Feed was provided as mashed feed. A 23/1h light/dark cycle was chosen. Raw materials used for the diets were free of mycotoxins. Respective mycotoxin diets were contaminated using T-2 toxin culture material provided by Biopure®. The detailed trial set-up can be taken from Table 1.
Table 1.Trial Set-Up
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Aim of the Trial
The aim of the trial was to evaluate the effect of 1.25 ppm T-2 toxin on performance and health of growing male broiler chickens. Additionally, the efficacy of 1 and 1.5 kg of Mycofix® Select to counteract T-2 toxin was tested.
Materials and Methods
The trial was made in the experimental units of the International Institute of Animal Investigation (iiia) in Queretaro, Mexico, under the surveillance of Dr. Miguel Forat. Ninety Ross 308 male broilers were weighed and randomly assigned to 6 groups, 1 bird per cage and 18 birds per group (Picture 1). The trial started at day 10 of age and lasted until day 39 of age of the birds. Prior to start, birds were fed a pre-starter diet, and during the trial a grower diet based on corn, soya paste and soy oil meeting the NRC requirements, with a crude protein of 20% and providing 3000 kcal. Feed was provided as mashed feed. A 23/1h light/dark cycle was chosen. Raw materials used for the diets were free of mycotoxins. Respective mycotoxin diets were contaminated using T-2 toxin culture material provided by Biopure®. The detailed trial set-up can be taken from Table 1.
Table 1.Trial Set-Up
| Group | T-2 toxin [1.25 ppm] | Mycofix® Select [1.0 kg/t] | Mycofix® Select [1.5 kg/t] |
|
1
|
no
|
no
|
no
|
|
2
|
yes
|
no
|
no
|
|
3
|
yes
|
yes
|
no
|
|
4
|
yes
|
no
|
yes
|
|
5
|
no
|
no
|
yes
|
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