US researcher evaluates antibiotic alternatives for controlling salmonella

Avian defensins have potent anti-bacterial activity
calendar icon 18 January 2023
clock icon 1 minute read

In a recent news release, USPOULTRY and the USPOULTRY Foundation announced the completion of a funded research project at Ohio State University in which the researcher evaluated potential antibiotic alternative approaches for controlling Salmonella in poultry.

Dr. Kichoon Lee, professor at Ohio State University, recently completed a research project that evaluated potential antibiotic alternative approaches for controlling Salmonella in poultry. Avian defensins have potent anti-bacterial activity. The expected long-term impact of the study was to help poultry breeders selectively breed chickens to have the most effective AvBD1 genotype; reduce the Salmonella population within the chicken gut; and ultimately produce a safer poultry product.

Although variations were identified in AvBD1 proteins among chicken populations, the in vivo and in vitro data did not show differences in anti-Salmonella activities.

The research was made possible in part by Simmons Foods and proceeds from the International Poultry Expo, part of the International Production & Processing Expo (IPPE). The research is part of the Association’s comprehensive research program encompassing all phases of poultry and egg production and processing. A summary of the completed project is below.

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