How can genomic selection be optimized for crossbreeding in pig and poultry breeding programs?

Wageningen researchers wrote a paper on how genomic selection can be optimized for the improvement of crossbred animals
calendar icon 18 October 2021
clock icon 3 minute read

Researchers from Wageningen University & Research have written a review paper on how genomic selection can be optimized for the improvement of crossbred animals.

Genomic selection

Livestock populations are continuously improved by a process called selection. With selection, breeders decide on which animals are allowed to reproduce, based on estimates of the animals’ genetic value. Nowadays, such estimates are obtained from statistical models that describe the relationship between the performance of animals (i.e. their phenotype) and the genetic variation in their DNA. This particular method of selection is called genomic selection, which requires phenotype and genotype marker data on a large number of reference animals.


Crossbreeding is the practice of mating animals from genetically distinct purebred lines to produce crossbreds, and is widely adopted in pig and poultry breeding. Genetic progress is realized in the purebred lines based on purebred phenotypes and genotypes, while the aim is to improve performance of the crossbreds. However, purebred and crossbred performance are not perfectly correlated, raising questions such as “Do we need to collect data on crossbreds?”, “Can we improve the statistical model?”, and “Where do the answers to these questions depend on?”. Researchers from Wageningen University & Research have summarized answers to these questions in a review paper that was recently published in the Journal of Animal Science.

Optimizing genomic selection for crossbred performance

The authors found that the optimal strategy is likely to vary across species, breeding programs, and traits. However, some general trends could be observed. First, when purebred data is used, the statistical model can be improved by accounting for genetic dominance effects. Second, genomic selection for crossbreeding may benefit from using crossbred instead of purebred data, but only when the genetic correlation between purebred and crossbred performance is lower than about 80%. Finally, even though genotyping is costly, it is advisable to collect genotypes of crossbred animals that are phenotyped. An important argument for this advice is that a single crossbred record can contribute to genetic improvement in all three or four parental lines, justifying the required investment.

This research was supported by the Netherlands Organisation of Scientific Research (NWO) and the Breed4Food consortium partners Cobb Europe, CRV, Hendrix Genetics, and Topigs Norsvin.

Wageningen University & Research

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